Knox Carey
Innovate ■ Create ■ Connect ■ Communicate
Skills
Education

PhD Electrical and Computer Engineering, Cornell University 1999
Thesis: Wavelet Coefficient Decay in Image Compression, Interpolation, and Transmission
Advisor: Sheila S. Hemami

MEng Electrical and Computer Engineering, Cornell University 1994
Thesis: An Unsupervised Neural Network for Detection of Biological Acoustic Transients
Advisor: Thomas W. Parks

BS Electrical and Computer Engineering, Cornell University 1992

Experience
Intertrust Technologies Corporation 1999–2001, 2003–2017
General Manager, Genecloud, 2013–2017
  • ■ Led team of 12 building Genecloud, a distributed system for trusted analysis of genomic data and other sensitive healthcare information
  • ■ General management responsibilities including strategy and business development, budget, staffing, product planning and technology architecture, marketing and evangelism
  • ■ Research and development in privacy, security, and scalability for bioinformatics in a distributed, multi-stakeholder environment
  • ■ Developed and implemented a compliance program to satisfy relevant regulations such as HIPAA/HITECH, the EU Data Protection Directive, and others
  • ■ Established thought leadership in the Global Alliance for Genomics and Health (GA4GH); chaired task teams within the Security Working Group and participated in long-term organizational planning
  • ■ Defined, architected, and led implementation of Beacon Project technology demonstrations involving stakeholders across the GA4GH
  • ■ Research on the balance between genomic privacy and data discoverability, resulting in publication, speaking engagements, and public challenges
  • ■ Initiated and managed partnerships and trial deployments with external companies and organizations, including academic and public health consortia, drug discovery companies
  • ■ Extensive public speaking, panels, and invited talks on the interplay between security, privacy, and accessibility of genomic data
  • ■ Intellectual property development in trusted distributed systems for genomics and other sensitive healthcare data
Vice President, Healthcare Initiatives, 2011–2013
  • ■ Led a team of five developing secure distributed systems for healthcare, including consumer-oriented “Quantified Self” data and genomics
  • ■ Designed technology prototypes for ingesting encrypted data from multiple sensors and performing analyses governed by policy
  • ■ Prototyped the use of trusted mobile agents to run computations locally and explored security/efficiency tradeoffs with cloud-based processing
  • ■ Developed business models and evangelized project with potential customers, including prominent consumer electronics companies
  • ■ Intellectual property development in trusted distributed systems for healthcare
Vice President, Technology, Asia-Pacific, 2008–2011
  • ■ Helped to establish Intertrust branch office in Beijing; recruited and led technical staff
  • ■ As technology head for the Asia-Pacific region, led customer-facing media, rights management, and security development efforts
  • ■ Working closely with customers, architected and prototyped a DRM Software-as-a-Service platform, which was subsequently productized
  • ■ Established joint research program with Tsinghua University, focused on rights management technology and standards for the Chinese market
  • ■ Extensive business development in greater China, Japan, Korea, and Southeast Asia
  • ■ Acted as a key liaison between the US content industry — particularly in Hollywood — and organizations in China
  • ■ Collaborative work with national standards efforts, particularly with the China DRM Forum, a standard launched by CCTV and SARFT. This work led to the adoption of the company's technology into the standards.
  • ■ Spearheaded technology collaborations with government enterprises, telecom operators, broadcasters, universities, and Internet companies across Asia
  • ■ Participated in business development efforts and intellectual property licensing
Director, Technology Initiatives, 2003–2008
  • ■ Managed technology partnerships with Hollywood studios and record labels
  • ■ Created the initial architecture for DECE/Ultraviolet, in close collaboration with Sony Pictures Entertainment
  • ■ Conceived original design of the rights management interoperability framework the Coral Consortium; co-chaired the architecture working committee and acted as liaison between Coral architecture, policy, and legal committees
  • ■ Designed demonstrations of the Coral DRM interoperability technology and led initiatives to build them for the Consumer Electronics Show, 2004–2007
  • ■ Extensive technology evangelism, training, public speaking, panels at venues like Digital Hollywood, the Connections conference, IEEE, etc.
  • ■ Led standardization efforts including Coral, Marlin, OMA, MPEG, and DLNA
  • ■ Intellectual property development in rights management and secure systems
Senior Architect, Technology Initiatives, 1999–2001
  • ■ Research and development in watermarking and signal security
  • ■ Participated in standardization efforts including MPEG and SDMI, establishing thought leadership in these organizations
  • ■ Implemented secure media systems based on Intertrust rights management technologies
  • ■ As part of the Media Technology Initiatives group, participated in business development, signing several key customers in the media space
  • ■ Led technical collaboration with several Hollywood studios and record labels, including the design of a secure VOD system with a major studio
SkyPilot Networks 2002–2003
Senior Architect, 2002–2003
  • ■ Developed and tested statistical models and algorithms for wireless mesh networking
  • ■ Implemented a multiresolution network simulation system which allowed designers to adjust the level of simulation detail by swapping in modules ranging from coarse statistical models to detailed simulation of wave propagation and TCP/IP network behavior
  • ■ Performed analysis of data collected from mesh networking hardware
Axiomatic Systems 2001–2002
Founder and CTO, 2001–2002
  • ■ Founded Axiomatic, a startup specializing in cross-platform interactive TV
  • ■ Researched the market using a combination of analyst research, financial modeling, and discussions with potential customers
  • ■ Created the business plan, executive brief, technical overview, and sales and funding presentations for the company
  • ■ Led the team that created the Axiomatic Virtual Platform, an authoring environment for rapid deployment of apps across multiple iTV platforms
  • ■ Designed and implemented interactive TV programs on the OpenTV, Liberate, MSTV, and MHP platforms
  • ■ Created an interactive version of Walking with Dinosaurs in collaboration with BBC America, which was deployed in California and received a “Bandies” award for Best New New Thing at the Western Cable Show, 2002
Sony Corporation 1998–1999
Senior Research Scientist, 1998–1999
  • ■ Conducted research and development in image and video processing systems for robust multiresolution image compression and transmission for packet based wireless networks
  • ■ Created new algorithms for image and video enhancement, interpolation, and error concealment and recovery
  • ■ Responsible for algorithm development from mathematical conception and testing to software prototyping and development
  • ■ Worked closely with hardware engineers to ensure realistic, implementable algorithms; helped to debug hardware
  • ■ Extensive study of high-definition and standard-definition video systems
  • ■ Wrote whitepapers and patent applications for intellectual property protection, as well as monthly technical reports detailing research activities
Aware Inc. 1994–1995
Member of Technical Staff, 1994–1995
  • ■ Conducted research in wavelet-based image compression, focusing on the interaction between visual smoothness and mathematical regularity; explored the ways in which image processing and compression affect visual smoothness and studied operational rate-distortion concerns in image compression
  • ■ Developed software in C and MATLAB for image compression and target recognition; compression work was integrated into a product release
Selected Publications
Federated Discovery and Sharing of Genomic Data using Beacons, with Marc Fiume et al. Nature Biotechnology, 2019 Mar; 37(3):220-224. https://www.nature.com/articles/s41587-019-0046-x
Registered Access: Authorizing Data Access, with Stephanie Dyke et al. European Journal of Human Genetics. 2018 Dec; 26(12):1721-1731. https://www.nature.com/articles/s41431-018-0219-y
Simplifying Research Access to Genomics and Health Data with Library Cards, with Moran Cabili et al. Scientific Data. 2018 Mar 14; 5:180039. https://www.nature.com/articles/sdata201839
A Community Effort to Protect Genomic Data Sharing, Collaboration and Outsourcing, with Shuang Wang et al. NPJ Genom Med. 2017 Oct 27; 2:33. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677972/
Addressing Beacon Re-Identification Attacks: Quantification and Mitigation of Privacy Risks, with Jean Louis Raisaro et al. Journal of the American Medical Informatics Association, 20 February 2017. https://academic.oup.com/jamia/article/3038412/Addressing
The Matchmaker Exchange: a platform for rare disease gene discovery, with A. Philippakis et al., Human Mutation, October 2015, 36(10):915-21. https://onlinelibrary.wiley.com/doi/full/10.1002/humu.22858
Securing Genomic Computations for Research and Clinical Decision Support, with Nevenka Dimitrova, et al. First International Symposium on Genome Privacy, Amsterdam, July 2014.
Persistent Security, Privacy, and Governance for Healthcare Information, with Jarl Nilsson and Steve Mitchell. USENIX 11, October 2011.
The Legal Environment for Copyright and Trust Management in China, with Lei Sun, Li Zhao, and Xin Tong. IEEE Conference on Consumer Communications and Networking (CCNC09), January 2009.
The Coral DRM Interoperability Framework, with Ton Kalker, Martin Rosner, and Jack Lacy. IEEE Conference on Consumer Communications and Networking (CCNC07), January 2007.
Coral and DRM Interoperability, with Rob Koenen and Jack Lacy. Europe-China conference on Intellectual Property and Digital Media (IPDM06), October 2006.
Regularity Preserving Image Interpolation, with Dan Chuang and Sheila Hemami. IEEE Transactions on Image Processing 8(9), September 1999, pp. 1293–1297.
Smoothness-Constrained Wavelet Image Compression, with Peter Heller and Sheila Hemami. IEEE Transactions on Image Processing 8(12), December 1999, pp. 1807–1811.
Recent Invited Talks
When you get your DNA scanned is your genetic privacy safe? CBC Radio's Quirks and Quarks, 24 June 2017.
Data Sharing: Patient Rights and Privacy, Personalized Medicine World Congress 2017 http://www.pmwcintl.com/2017sv/sessionthemes-data-sharing-patient-rights-and-privacy.
Access versus Privacy: A False Dichotomy, Personalized Medicine World Congress 2016 https://vimeo.com/album/3801806/video/156680934.
Impediments to Interoperability: Why Can't We All Just Get Along?, Human Genome Variation Conference, 2015.
Squaring the Circle: Access and Genomic Privacy, Intertrust Technologies Lecture Series, 2015 http://www.youtube.com/watch?v=UdBc53-xCWY.
Preserving Privacy for Genomic Information in the Cloud, IAPP European Data Protection Congress, 2014.
Patents
Classified adaptive Error Recovery Method and Apparatus, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,351,494.
Source Code Shuffling to Provide for Robust Error Recovery, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,389,562.
Method and Apparatus for Robust Coding of Bitstreams using Rotation, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,473,876.
Time-Varying Randomization for Data Synchronization and Implicit Information Transmission, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,493,842.
Classified Adaptive Error Recovery Method and Apparatus, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,522,785.
Data Transformation for Explicit Transmission of Control Information, with Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,539,517.
Method and Apparatus for Recovery of Encoded Data Using Central Value, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,549,672.
Time-Varying Randomization for Data Synchronization and Implicit Information Transmission, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,553,381.
Method and Apparatus for Past and Future Motion Compensation, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 6,754,371.
Data Transformation for Explicit Transmission of Control Information, with Kondo, Y. Fujimori, and J. Carrig. US Patent No. 7,080,312.
Method and Apparatus for Recovery of Encoded Data using Central Value, with T. Kondo, Y. Fujimori, and J. Carrig. US Patent No. 7,224,838.
Determining whether a digital rights management system's native license is valid, with Ton Kalker, US Patent No. 8,060,444.
Bioinformatic processing systems and methods, with Jarl Nilsson, US Patent No. 9,306,981
Distributed computation systems and methods, with Jarl Nilsson, US Patent No. 9,503,512
Secure computing systems and methods, with Jarl Nilsson and Bart Grantham, US Patent No. 9,558,322
Information security systems and methods, with Jarl Nilsson, US Patent No. 9,589,110
Bioinformatic processing systems and methods, with Jarl Nilsson, US Patent No. 9,710,597
Information security systems and methods, with Jarl Nilsson, US Patent No. 10,009,384
Secure computing systems and methods, with Jarl Nilsson, US Patent No. 10,083,277
Bioinformatic processing systems and methods, with Jarl Nilsson, US Patent No. 10,127,354
Data communication and storage systems and methods, with Jarl Nilsson, Bart Grantham, Eric Swenson, US Patent No. 10,409,791
Distributed computing systems and methods, with Jarl Nilsson, US Patent No. 10,423,453
Bioinformatic processing systems and methods, with Jarl Nilsson, US Patent No. 10,522,244
Technologies
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